| Hamartoma (Chondrofibrolipoma)
|
Etiology
• Unknown.
• Although previously called hamartoma, these lesions develop over years and
are not congenital.
|
Pathogenesis
• Unknown,
|
Epidemiology
• Patients over 40; women outnumber men
2:1
• Rare cause of solitary lesion detected on radiographic studies
|
General Gross Description
• Solitary nodule or "coin lesion"
• May be firm and glassy depending on the amount of cartilage within the
lesion
•Examples:
|
General Microscopic Description
• Composed of mature cartilage, fibrous tissue, and fat as well as
occasional blood vessels and respiratory epithelium.
•Examples:
|
Clinical Correlation
• Often found on
chest xray or other radiographic study and diagnosed as part of an
evaluation to rule out carcinoma.
|
References
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 727.
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| Hamartoma (Chondrofibrolipoma)
| | Synopsis by: Melinda Sanders M.D. (T28000M75500)[130]
| |