| Lymphoma
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Etiology
•Unknown
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Pathogenesis
•Theoretically, the result of a mutated neoplastic
lymphocyte proliferating as a clone; some are associated with specific translocations.
•Possible occurrence in immunosuppressed persons.,
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Epidemiology
•The heart is involved by metastatic cancers and
lymphomas in 5-10% of cases.
•Primary lymphomas of the heart (without involvement
of lymph nodes or other organs) are rare.
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General Gross Description
•May involve any and all layers of the heart and any
and all chambers of the heart.
•A mass thickening or distortion of the shape of
involved anatomy.
•The cut surface appears either white or shades of
gray to light tan, depending on cytological features.
•Tumor cells with sparse cytoplasm appear white; other
shades vary with amount and features of cytoplasm.
•Examples:
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General Microscopic Description
•The histology is that of the spectrum of Hodgkins
disease and non-Hodgkins lymphomas.
•Examples:
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References
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 569-571 and 633-666.
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| Lymphoma
| | Synopsis by: J. Hasson, MD (T31000M95903)[300]
| |