Liver abscess can result from infections or penetrating
injuries to the liver.
As with abscess elsewhere, an abscess of the liver
is a circumscribed lesion with central liquefactive
necrosis containing organisms and a surrounding area of hyperemia and
With improved care of intra-abdominal sepsis, pyogenic abscesses of the liver are
In developing countries, they are somewhat more common, usually as a result of parasitic
|General Gross Description|
When the infection spreads to the liver through the
vascular route, abscesses can be multiple.
More commonly, when they result from spread of
infection from elsewhere, abscesses are solitary.
A common lesion in developing countries is an amebic
liver abscess; the ameba are carried from the colon.
Amebic liver abscesses can be very large and have a
typical chocolate color and consistency.
They are also referred to an "anchovy paste" abscesses.
|General Microscopic Description|
Histologically, the lesions are characterized by a
central of liquefactive necrosis with degenerating
and necrotic liver cells and inflammatory cells.
Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 856
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|Synopsis by: T.V.Rajan, M.D., Ph.D. (T56000M41740)