| Congenital Mesoblastic Neprhoma
|
Etiology
•Unknown.
|
Pathogenesis
•Unknown.,
|
Epidemiology
•Usually
discovered in the first 3 months of life.
•Believed to be congenital and
may be discovered prior to birth by ultrasound studies.
•Has been
reported in children with the Beckwith-Wiedemann syndrome.
•There is no
sex predilection.
|
General Gross Description
•This renal tumor is usually solitary and
unilateral.
•On cut surface the tumor is usually light tan, fleshy and
has ill-defined peripheral borders, blending into the adjacent renal
parenchyma.
•Examples:
|
General Microscopic Description
•The tumor is microscopically monomorphic, composed of spindled shape
cells.
•The tumor cells resemble fibroblasts with scant interstitial
collagen.
•At the periphery, the tumor extends into the adjacent renal
parenchyma with minimal compression and distortion.
•Examples:
|
References
•Murphy WM, Beckwith JB, and Farrow GM. Tumors of the Kidney, Bladder, and Related Urinary Structures,
Washington: AFIP, 1994,
pp. 55-67.
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| Congenital Mesoblastic Neprhoma
| | Synopsis by: Harold Yamase M.D. (T71000M88000)[235]
| |