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Congenital Mesoblastic Neprhoma
Etiology

Unknown.
Pathogenesis

Unknown.,
Epidemiology

Usually discovered in the first 3 months of life.
Believed to be congenital and may be discovered prior to birth by ultrasound studies.
Has been reported in children with the Beckwith-Wiedemann syndrome.
There is no sex predilection.
General Gross Description

This renal tumor is usually solitary and unilateral.
On cut surface the tumor is usually light tan, fleshy and has ill-defined peripheral borders, blending into the adjacent renal parenchyma.
•Examples:
Congenital Mesoblastic Nephroma
General Microscopic Description

The tumor is microscopically monomorphic, composed of spindled shape cells.
The tumor cells resemble fibroblasts with scant interstitial collagen.
At the periphery, the tumor extends into the adjacent renal parenchyma with minimal compression and distortion.
•Examples:
References

Murphy WM, Beckwith JB, and Farrow GM. Tumors of the Kidney, Bladder, and Related Urinary Structures, Washington: AFIP, 1994, pp. 55-67.

For Most Current Information Search Medline at National Library of Medicine
This link will directly take you to the relevant new literature
Congenital Mesoblastic Neprhoma
Synopsis by: Harold Yamase M.D. (T71000M88000)[235]
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