| Squamous Metaplasia of Bladder
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Etiology
The etiology of squamous metaplasia is dependent upon the
underlying pathologic process, i.e, bladder calculi, extrophy of the
bladder, schistosomiasis.
Probably normal in women.
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Pathogenesis
The normal transitional epithelium will undergo
squamous metaplasia as an adaptive change to chronic irritation, such as
from bladder calculi.,
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Epidemiology
The epidemiology is dependent on the underlying disease
process.
Squamous metaplasia is found in a large percentage of women with no abnormalities.
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General Gross Description
There is no striking gross changes to the epithelial
lining of the bladder. There may be a perception that the epithelial
lining is paler and thicker than normal.
Examples:
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General Microscopic Description
The normal
transitional epithelium of the bladder is replaced by stratified squamous
epithelium. Examples:
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References
Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 48
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| Squamous Metaplasia of Bladder
| | Synopsis by: Harold Yamase M.D. (T74000M73220)[177]
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