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Granulomatous orchitis
Etiology

Unknown.
Pathogenesis

Unknown.
Some speculate that the disease may have an autoimmune basis.,
Epidemiology

Middle age males.
More frequently in African-Americans.
Some cases are associated with urinary tract infections, history of prostatectomy, inguinal hernia repair and trauma.
General Gross Description

The testis is enlarged.
The cut surface is vaguely nodular, yellowish, and hard.
Testicular involvement may be total or partial.
•Examples:
Granulomatous Orchitis
General Microscopic Description

There is inflammation consisting of lymphocytes, plasma cells, macrophages, fibroblasts and scattered multinucleated giant cells.
•Examples:
Clinical Correlation

Painful unilateral testicular enlargement in middle aged men.
There may be associated fever.
References

Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, p. 1013. Mostofi FK and Price EB editors.

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Granulomatous orchitis
Synopsis by: Harold Yamase M.D. (T78000M44000)[238]
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