| Tubercuous Epididymitis
|
Etiology
•Infection by Mycobacterium
tuberculosis.
|
Pathogenesis
•The reader is referred to a general discussion on the
pathogenesis of tuberculosis. In short, pathogenesis relates to the
organism's ability to escape the killing mechanisms of macrophages and its
ability to induce delayed type hypersensitivity. Much of the damage to
tissues is due to the patient's hypersensitivity reaction to persistent
organisms.,
|
Epidemiology
•Usually a
complication of pulmonary and renal tuberculosis. The reader is referred to
a general discussion on tuberculosis.
|
General Gross Description
•The epididymis is enlarged and indurated and usually associated with
testicular involvement by the same disease process.
•Examples:
|
General Microscopic Description
•The histologic
features are the same as for other organs.
•The inflammation is
granulomatous in character with caseous necrosis, chronic inflammatory
cells, epithelioid histiocytes and occasional multinucleated giant cells.
•Examples:
|
Clinical Correlation
•Tuberculous involvement of the epididymis is usually secondary to renal or
pulmonary tubulerculosis.
|
References
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1014.
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| Tubercuous Epididymitis
| | Synopsis by: Harold Yamase M.D. (T79000M44000)[244]
| |