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Embryonal Carcinoma
Etiology

Unknown.
The tumor is a germ cell malignancy.
Pathogenesis

Unknown.
The tumor is a germ cell malignancy.,
Epidemiology

Affects males in the third and fourth decades of life.
General Gross Description

On cut section, the tumor frequently shows irregular areas of necrosis and hemorrhage.
The tumor is variably demarcated from surrounding testis and structures.
•Examples:
General Microscopic Description

Histologically the tumor shows variable epithelial features including glandular and papillary structures and variable areas of undifferentiated sheets of tumor cells.
There are often areas of tumor necrosis and associated hemorrhage.
Cytologically, tumor cells show hyperchromatic pleomorphic nuclei with prominent sometimes multiple nucleoli.
•Examples:
Embryonal Carcinoma
References

Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1017-1018.
Urological Pathology, Murphy WM (ed), Philadelphia: Saunders, 1989, pp. 330-336.

For Most Current Information Search Medline at National Library of Medicine
This link will directly take you to the relevant new literature
Embryonal Carcinoma
Synopsis by: Harold Yamase M.D. (T78000M90703)[466]
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