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Endometriosis
Etiology

unknown
Pathogenesis

hypotheses include retrograde menstruation with implantation, metaplasia of the pelvic peritoneum (Mullerian derivative) or lymphovascular invasion,
Epidemiology

reproductive age women esp 4th and 5th decade
often associated with infertility without evidence of actual tubal obstruction
General Gross Description

cortical surface may be dull with adhesions
cysts contain old brown blood "chocolate"
generally unilocular
granular, shaggy brown lining
also affects pelvic and uterine ligaments, cul-de-sac, peritoneum, abdominal scars and occasionally distant sites
•Examples:
General Microscopic Description

endometrial glands and/or
endometrial stroma and/or
hemosiderin laden macrophages (2 out of above 3)
usually abundant scar
•Examples:
Endometriosis of  Ovary (20X) Endometriosis of Ovary (40X)
References

Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1054-1055

For Most Current Information Search Medline at National Library of Medicine
This link will directly take you to the relevant new literature
Endometriosis
Synopsis by: Melinda Sanders M.D. (T87000M76500)[36]
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