| Endometrial Stromal Sarcoma
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Etiology
•unknown
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Pathogenesis
•unknown,
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Epidemiology
•accounts for approximately 1-2% of endometrial
malignancies
•post-menopausal patients
•not associated with estrogen excess
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General Gross Description
•intraluminal, friable, hemorrhagic gray white mass
•may be fleshy
•Examples:
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General Microscopic Description
•proliferation of stromal cells without glands
•poorly circumscribed with infiltrative borders
•nuclei are hyperchromatic and pleomorphic with scant cytoplasm
•mitoses are abundant in the high grade neoplasms
•Examples:
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References
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1063
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| Endometrial Stromal Sarcoma
| | Synopsis by: Melinda Sanders M.D. (T84000M89303)[21]
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