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Metastatic Adenocarcinoma
Etiology

Unknown.
Pathogenesis

Arrive via systemic circulation
Unknown why lung carcinoma has predilection for adrenals,
Epidemiology

Up to 25% of patients with metastatic carcinomas
Lung and breast predominate
Also GI tract, thyroid, kidney, other adrenal
General Gross Description

May be cortical or medullary, tan with or without hemorrhage or necrosis.
•Examples:
Metastatic Adenocarcinoma Metastatic Adenocarcinoma (Cross Section)
General Microscopic Description

Resembles primary site
•Examples:
Clinical Correlation

Requires chemotherapy to treat.
May be associated with mild adrenal failure.
References

Diagnostic Surgical Pathology, 2d edition, Sternberg SS (ed). Philadelphia: Lippincott-Raven,1996, pp. 585-6.

Search Medline at National Library of Medicine
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Metastatic Adenocarcinoma
Synopsis by: Melinda Sanders M.D. (T93000M81406)[444]
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