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| Normal Bone Marrow | ||
| Etiology • Not applicable. | ||
| Pathogenesis • Not applicable., | ||
| Epidemiology • Not applicable. | ||
| General Gross Description • Red in the young individual; yellow and fatty in the older individual •Examples: | ||
| General Microscopic Description • In adult life the ratio of marrow elements to fat is 1:1 • Admixture of myeloid cells and erythroid cells in a ratio of 3:1 • Approximately 60% of cells are myeloid precursors including promyelocytes, metamyelocytes, myelocytes (with specific granules) and immature basophils, eosinophils and neutrophils • Approximately 20% of cells are erythroid precursors with round dark nuclei • Ten percent of cells are lymphoid including plasma cells • Scattered megakaryocytes are also seen • With age the marrow to fat ratio declines •Examples: | ||
| Clinical Correlation •Not applicable | ||
| References • Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 585-586. Please be patient during transfer. Medline will open in a new window. To return, close the Medline Window Normal Bone Marrow
| Synopsis by: Melinda Sanders M.D. (T06000M00100)[97]
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