| Infarct
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Etiology
• Thrombosis of splenic arteries, usually embolic
• Non-thrombotic decrease in blood flow in very large spleens
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Pathogenesis
• Obstruction or compromise of blood flow with necrosis of distal tissue,
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Epidemiology
• Associated with endocarditis
• Associated with hematologic conditions resulting in very enlarged spleens, such as leukemia
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General Gross Description
• White, firm lesions which are triangular
• Base of triangle at capsule
•Examples:
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General Microscopic Description
• Necrotic, hemorrhagic tissue which does not organize
•Examples:
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Clinical Correlation
• May present with sudden onset of pain
• Usually incidental
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References
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 670.
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| Infarct
| | Synopsis by: Melinda Sanders M.D. (T07000M54700)[414]
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