| Trauma (Rupture)
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Etiology
• Trauma.
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Pathogenesis
• Relatively unsupported parenchyma, especially if congested, becomes lacerated,
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Epidemiology
• Associated with blunt or crushing injury
• Relatively trivial injury can result in rupture if spleen is enlarged and extending below costal margin as in portal hypertension, splenic sequestration syndromes, mononucleosis or other infection, and leukemia.
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General Gross Description
• Hemorrhage which may be contained by capsule
• Irregularly lacerated tissue
• Appearance of unlacerated spleen may reflect underlying pathology
•Examples:
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General Microscopic Description
• Disrupted parenchyma with hemorrhage.
• Underlying pathology may be revealed.
•Examples:
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Clinical Correlation
• Treated by resection
• Rupture results in life-threatening intraperitoneal hemorrhage
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References
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 905-7.
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| Trauma (Rupture)
| | Synopsis by: Melinda Sanders M.D. (T07000M14430)[416]
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