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| Angiofibroma | ||
| Etiology • Unknown • Increases in size under the influence of testosterone | ||
| Pathogenesis • Unknown, | ||
| Epidemiology • Predilection for teenage boys (peak incidence at age 15) • Rarely ever seen in girls, if at all | ||
| General Gross Description • Firm, fibrous masses • Well circumscribed •Examples: | ||
| General Microscopic Description • Numerous vascular spaces embedded in stroma which is collagenized • Spaces generally lined by single layer of endothelium •Examples: | ||
| Clinical Correlation • Present with nasal obstruction and bleeding, as arise from lateral nasopharynx • May bleed profusely with surgery, which is treatment of choice • May need chemotherapy if surgery cannot remove intracranial extension | ||
| References • Sternberg SS ed. Diagnostic Surgical Pathology, 2d edition, Lippincott-Raven; Philadelphia. 1996, pp. 874-5. Please be patient during transfer. Medline will open in a new window. To return, close the Medline Window Angiofibroma
| Synopsis by: Melinda Sanders M.D. (T21000M91600)[434]
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