Bacteria, i.e. staph., strep., pseudomonas, others.
Fungi, i.e. candida, aspergillus, others
Infective Endocarditis: Friable vegetations embolize via coronary arteries causing a focal myocarditis, which can progress to abscesses.
Infection of a valve prosthesis along valve ring suture may progress to a valve ring abscess extending into myocardium.
Opportunistic infections in immunocompromised host with septicemia and metastatic abscesses in multiple organs including heart, lung, brain and kidneys.,
Complicating infective endocarditis, infection of a prosthetic valve, immunosuppresion, or rarely occurring in an otherwise well individual with a secondary pyemia.
|General Gross Description|
A sharply defined rounded lesion contaning a thick viscid fluid. Often white, but can also be shades of grey and yellow.
Size may vary from microscopic dimensions to visible lesions up to as much as 3 cm in diameter.
Chronic abscesses may have a we1l defined capsule of reactive fibrosis.
|General Microscopic Description|
Neutrophils compose the purulent contents.
Bacteria and/or fungi may be identified with or without the aid of special stains.
Cotran RS et.al.: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 550-4
Harrison's Principles of Internal Medicine, 13th Edition: Isselbach et. al. (eds). New York, McGraw-Hill, 1994, pp. 494-8
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||Synopsis by: J. Hasson, MD (T32000M41740)