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| Pleural Adhesions | ||
| Etiology • Usually the sequel to inflammatory or fibrinous pleuritis • May also be associated with underlying pulmonary fibrosing disease • Asbestos may caused localized pleural fibrosis | ||
| Pathogenesis • In response to organisms or other stimulus pleural edema develops • Fibrinous exudate forms • Organization of the exudate by vessel ingrowth and fibroblast proliferation results in adhesions, | ||
| Epidemiology • Dependent on the epidemiology of the underlying pulmonary disease | ||
| General Gross Description • Fibrous adhesions are gray, membranous and dull • May be quite dense and difficult to dissect •Examples: | ||
| General Microscopic Description • Composed of fibroblasts and collagen •Examples: | ||
| Clinical Correlation • Usually incidental finding at autopsy • Massive adhesions may lead to restriction of pulmonary expansion with symptoms of restrictive pulmonary disease. | ||
| References • Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 728-730 • Saldana MJ. Pathology of pulmonary Disease. Philadelphia: J.B. Lippincott, 1994, pp. pp. 868-9. Please be patient during transfer. Medline will open in a new window. To return, close the Medline Window Pleural Adhesions
| Synopsis by: Melinda Sanders M.D. (T28000M49400)[252]
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