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Normal Esophagus
Etiology

Not applicable.
Pathogenesis

Not applicable.,
Epidemiology

Not applicable.
General Gross Description

Extends from cricoid cartilage in the posterior mediastinum through the diaphragm to join the stomach
Endoscopic distance measured from the incisors to the GE junction varies from 38-43 cms.
Supplied by inferior thyroid artery, bronchial arteries, intercostals and aorta, as well as left gastric and inferior phrenic arteries
Drains into azygous system in upper 2/3; some portal drainage for distal esophagus
•Examples:
Normal Distal Esophagus Normal Esophagus - Endoscopy Normal Esophagus - Endoscopy
General Microscopic Description

Non-keratinizing stratified squamous mucosa
Basal layer normally 10-15% of thickeness
Scattered intraepithelial lymphocytes and Langerhans cells are seen
Lamina propria which may contain mucus secreting glands lies on muscularis mucosae
Submucosa contains submucosal glands overlying muscularis propria and then delicate fascia.
•Examples:
Normal esophageal and tracheal mucosa normal esophageal and tracheal mucosa Normal esophageal wall Normal esophageal mucosa Normal Esophageal Mucosa x40 Normal Gastro-esophageal Junction
Clinical Correlation

Not applicable.
References

Histology for Pathologists. Sternberg SS ed. New York: Raven Press, 1992. pp. 516-527.

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Normal Esophagus
Synopsis by: Melinda Sanders M.D. (T62000M00100)[542]
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