Prev
GI Menu
PathWeb Home
©
Feed Back
About
Next
Normal Stomach
Etiology

Not applicable.
Pathogenesis

Not applicable.,
Epidemiology

Not applicable.
General Gross Description

Located in the left upper quadrant connecting esophagus and duodenum
Four zones including cardia (transition from esophagus), fundus or body, antrum and pylorus
Supplied by celiac axis, hepatic artery, and splenic artery
•Examples:
Normal stomach Normal stomach - Endoscopy
General Microscopic Description

Tall columnar epithelium covers surface with intervening pits (foveolae, crypts)
Glands emptying into pits vary with location in stomach
Cardiac and antral glands are mucin secreting with occasional parietal cells; glands and pits occupy approximately 1/2 the mucosal thickness
Fundic glands occupy 1/4 mucosal thickness, straight, and have abundant chief cells with basal nuclei and gray-blue cytoplasm as well as numerous parietal cells with deep pink cytoplasm
Lamina propria contains lymphocytes, fibroblasts and histiocytes; intraepithelial lymphocytes are rare; plasma cells are not considered normal
Muscularis mucosa above submucosa which lies on muscularis propria and serosa
•Examples:
Gastric Fundus x4 Normal Cardia x40 Normal gastric fundus x10 Normal gastric fundus x40 Normal Gastric Antral Mucosa x10 Normal Gastric Antrum x20 Normal Gastric Antrum x40 Normal Gastric Antrum x40
Clinical Correlation

Not applicable.
References

Histology for Pathologists. Sternberg SS ed. New York: Raven Press, 1992. pp. 533-539.

Search Medline at National Library of Medicine
Please be patient during transfer. Medline will open in a new window. To return, close the Medline Window
Normal Stomach
Synopsis by: Melinda Sanders M.D. (T63000M00100)[543]
Prev
PathWeb Home
©
Feed Back
About
Next