| Mycobacterium Avium Complex Infection
|
Etiology
• Mycobacterium avium and other closely associated organisms including M. intracellulare, and M. scrofulaceum, ubiquitous in the environment.
|
Pathogenesis
• Organisms disseminate throughout the body
• Accumulate within macrophages in the lamina propria,
|
Epidemiology
• Found in immunocompromised host, specifically patients with HIV infection.
|
General Gross Description
• May appear normal.
•Examples:
|
General Microscopic Description
• Macrophages within lamina propria contain foamy macrophages.
• Numerous organisms can be identified within the macrophages with acid fast stains
• Little to no inflammatory response.
• Superficial resembalnce to Whipple's disease
•Examples:
|
Clinical Correlation
• Part of disseminated disease.
• Drug regimens to treat as well as prevent disease available.
|
References
• Diagnostic Surgical Pathology, 2d edition, Sternberg SS (ed). Philadelphia: Lippincott-Raven,1996, pp. 1335.
Search Medline at National Library of Medicine
Please be patient during transfer. Medline will open in a new window. To return, close the Medline Window
| Mycobacterium Avium Complex Infection
| | Synopsis by: Melinda Sanders M.D. (T64000E20170)[530]
| |