| Persistent Cloaca
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Etiology
•Unknown.
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Pathogenesis
•The abnormality results from failure of the urorectal septum to separate the primitive urogenital sinus from the hindgut.,
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Epidemiology
•Developmental disorder detected prenatally or at birth.
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General Gross Description
•The diagnosis rests on the gross demonstration of a common structure serving as bladder and rectum.
•Examples:
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General Microscopic Description
•Not applicable.
•Examples:
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Clinical Correlation
•Associated anomalies may include imperforate anus, abscence of genital and urinary orifices, megacolon, megaureters, renal dysplasia, renal agenesis.
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References
•Textbook of Fetal and Perinatal Pathology. Wigglesworth JS and Singer DB (eds) Cambridge: Blackwell, 1989, pp. 1163-4.
•Langman's Medical Embryology, 6th edition. 1990. Sadler TW. Baltimore: Williams and Wilkins. pp. 75, 255, 268.
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| Persistent Cloaca
| | Synopsis by: Harold Yamase M.D. (T74000M20000)[480]
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