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Leiomyosarcoma of Prostate
Etiology

Unknown.
Pathogenesis

Unknown.,
Epidemiology

Rare, however leiomyosarcomas are the most common sarcomas that involve the prostate gland in the adult.
Most patients are between 40 and 70 years old.
General Gross Description

Median size of reported cases is 5 cm.
Cut surface is tan and fleshy.
•Examples:
Leiomyosarcoma of Prostate
General Microscopic Description

The tumor is a spindle cell neoplasm.
The greater the nuclear pleomorphism and the greater the number of mitotic figures, the more certain one is of malignancy.
Because smooth muscle tumors are rare in the prostate, criteria distinquishing leiomyosarcoma from leiomyoma have not been established.
•Examples:
References

Epstein JI. Prostate Biopsy Interpretation. New York: Raven Press, 1989. pp.223-224.

For Most Current Information Search Medline at National Library of Medicine
This link will directly take you to the relevant new literature
Leiomyosarcoma of Prostate
Synopsis by: Harold Yamase M.D. (T77100M88903)[474]
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