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Normal Ovary
Etiology

Not applicable.
Pathogenesis

Not applicable
,
Epidemiology

Not applicable
General Gross Description

Measure 2-5 x 1.5-3.0 x 0.5 -1.5 cms.
Weigh 8 grams
Attached by mesovarium to posterior broad ligament, by utero-ovarian ligament to the uterine cornu, and by the infundibulopelvic ligament to the lateral pelvic walls
Smooth external surface of prepubertal ovary becomes convoluted and scarred with age
Cut surfaces show ill defined outer cortex and inner medulla
Vividly yellow corpus luteum; white irregular corpora albicans
Vascular supply derives from ovarian artery and ascending branch of the uterine artery
Venous drainage into the ovarian veins
Lymphatic drainage parallels ovarian vessels
•Examples:
General Microscopic Description

Covered by focally pseudostratified epithelium often difficult to see
Stroma of spindly fibroblast-like cells and may contain luteinized cells, decidualized cells, smooth muscle cells, and neuroendorine cells
Granulosa cells formed by birth with no lipid content until just prior to ovulation
Call-Exner bodies (cavities in the graulosa cell layer) contain basal lamina
Theca cells derive from stroma
Ova are present in follicles
Post-ovulation mass of yellow luteinized cells forms corpus luteum
Scarring of corpus luteum results in fibrotic corpous albicantia.
•Examples:
Normal Ovary -  Surface Epithelium Normal Ovary -  Surface Epithelium (Hi Pow) Normal Ovary - Corpus Albicans Normal Ovary - Corpus Luteum Normal Ovary -  Corpus Luteum (20X) Normal Ovary - Corpus Luteum (40X)
Clinical Correlation

Not applicable
References

Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1034

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Normal Ovary
Synopsis by: Melinda Sanders M.D. (T87000M00100)[257]
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