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| Fibroma-Thecoma | ||
| Etiology • unknown | ||
| Pathogenesis • unknown, | ||
| Epidemiology • rare neoplasm | ||
| General Gross Description • smooth external surface • firm, tan white interior with interlacing bundles of fibers • very large neoplasms may have cystic spaces •Examples: | ||
| General Microscopic Description • bland, spindle cells resembling fibroblasts • some collagen production • occasional lipid laden thecal cells may be seen •Examples: | ||
| Clinical Correlation • reproductive age or perimenopausal • 40% show associated ascites (Meig's syndrome) clinically similar to ovarian adenocarcinoma • ascites disappears with removal of the primary • may be associated with basal cell nevus syndrome • rare malignancy termed fibrosarcoma | ||
| References • Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1075-6 Please be patient during transfer. Medline will open in a new window. To return, close the Medline Window Fibroma-Thecoma
| Synopsis by: Melinda Sanders M.D. (T87000M88100)[51]
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