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Pregnancy Luteoma
Etiology

Pregnancy
Pathogenesis

HCG induced proliferation of stromal cells
? pre-existent endocrine dysfunction,
Epidemiology

Reproductive age group
African American
Multiparous
May be associated with virilism of mother(25%)
Virilized infants in 2/3 of virilized mothers
General Gross Description

May be yellow, brown or gray
Solid or with areas of hemorrhage
May be multiple
•Examples:
General Microscopic Description

Luteinized large cells with abundant eosinophilic cytoplasm
Nuclei are regular
•Examples:
Luteoma (10X) Luteoma (20X) Luteoma (40X)
Clinical Correlation

Benign, may recur in subsequent pregnancies.
References

Blaustein's Pathology of the Female Genital Tract, 4th ed. Kurman RJ (ed). New York: Springer-Verlag, 1994, pp. 495-497.
Clement PB,Tumor-like lesions of the ovary associated with pregnancy. Int J Gynecol Pathol, 1993, 12(2), 108-115.

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Pregnancy Luteoma
Synopsis by: Melinda Sanders M.D. (T87000M86100)[272]
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