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| Immature (Malignant) Teratoma | ||
| Etiology • unknown | ||
| Pathogenesis • proliferation of a meiotic germ cell, | ||
| Epidemiology • rare neoplasm | ||
| General Gross Description • smooth external surface • predominantly solid although may be cystic • necrosis and hemorrhage • hair, keratinaceous debris, bone and cartilage •Examples: | ||
| General Microscopic Description • IMMATURE (FETAL) tissues from all three germ cell layers • immature neural elements are common and may correlate with outcome •Examples: | ||
| Clinical Correlation • women under 21 with abdominal pain and enlargement • Stage I confined to the ovary, II confined to the pelvis, III confined to peritoneal cavity, IV distant metastases • treat Stage I with surgery and chemotherapy as warranted | ||
| References • Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. pp. 1073 Please be patient during transfer. Medline will open in a new window. To return, close the Medline Window Immature (Malignant) Teratoma
| Synopsis by: Melinda Sanders M.D. (T87000M90803)[48]
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