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| Normal Secretory Endometrium | ||
| Etiology •not applicable | ||
| Pathogenesis •not applicable, | ||
| Epidemiology •not applicable | ||
| General Gross Description •tan, soft, measuring up to 4 mm in thickness •Examples: | ||
| General Microscopic Description •KEY feature is the presence of glandular secretions •glands become tortuous with progression of secretions from basal vacuoles (d 17-18), supranuclear vacuoles (d 19-20), active intraluminal secretion (d 21-22) •spiral arteries become prominent (d 21-22) and develop predecidual stromal cuffing (d23-24) •stromal edema develops (d21-22) with subcapsular (d 25) and full thickness predecidual change (d 26) •leukocytic infiltrate pronounced by d 27-8. •Examples: | ||
| Clinical Correlation •normal in the luteal phase of the menstrual cycle •maturation of the epithelium previously treated with estrogen by the influence of progesterone •menstruation begins with the loss of progesterone and vasoconstriction of spiral arteries | ||
| References • Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1035-6 Please be patient during transfer. Medline will open in a new window. To return, close the Medline Window Normal Secretory Endometrium
| Synopsis by: Melinda Sanders M.D. (T84000M79320)[14]
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