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| Polyp | ||
| Etiology •unknown, some association with tamoxifen a systemic anti-estrogen with mixed effects on the uterus •may be associated with increased unopposed estrogen | ||
| Pathogenesis •unknown •? local hyperresponsiveness to estrogen with failure to respond to progesterone, | ||
| Epidemiology •perimenopausal women | ||
| General Gross Description •sessile or pedunculated soft tan masses •0.5 cm to 3.0 cm in diameter, usually •may protrude through cervical os •Examples: | ||
| General Microscopic Description •glands varying from proliferative to hyperplastic mixed with glands showing cystic dilatation with secretion •dense fibrous stroma •collarette of blood vessels with fibrotic walls •occasionally glands may be atrophic •Examples: | ||
| Clinical Correlation •irregular menses or asymptomatic •treatment with removal is generally curative | ||
| References • Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1059 Please be patient during transfer. Medline will open in a new window. To return, close the Medline Window Polyp
| Synopsis by: Melinda Sanders M.D. (T84000M76800)[16]
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