| Trophoblast Inclusions
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Etiology
• Unknown.
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Pathogenesis
• Due to cross sections of deeply infolded villous contours,
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Epidemiology
• Increased in triploid gestations, particularly partial moles.
• May also be increased in aneuploid gestations with other chromsome counts
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General Gross Description
• Microscopic finding
•Examples:
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General Microscopic Description
• Intravillus finding composed of syncytio- and/or cytotrophoblast
• Maternal blood may be contained within the inclusion
•Examples:
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Clinical Correlation
• Outcome dependent on underlying pathology
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References
• Benirschke K, Kaufmann P. Pathology of the human placenta, 3rd ed. New York: Springer-Verlag, 1995, pp. 670-671.
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| Trophoblast Inclusions
| | Synopsis by: Melinda Sanders M.D. (T88100M20000)[425]
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