| Circumvallate Placentation
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Etiology
• Unknown
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Pathogenesis
• Rupture of membranes with or without ongoing leakage results in smaller amnion sac than width of the placental disk,
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Epidemiology
• Associated with amnion rupture and extramembranous pregnancy
• May also be associated with maternal smoking
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General Gross Description
• Membranes insert central to the edge of the placental disk
• The edge of the chorionic plate is not the edge of the placental disk
• The surface of the placental disk consists of necrotic decidua
•Examples:
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General Microscopic Description
• Section reveals old hemorrhage and necrotic decidua beneath the folded membranes
•Examples:
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Clinical Correlation
• May be associated with positional deformities of the fetus and hypoplasia of the lungs if outside the amnionic sac
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References
• Benirschke K, Kaufmann P. Pathology of the human placenta, 3rd ed. New York: Springer-Verlag, 1995, pp. 305-7.
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| Circumvallate Placentation
| | Synopsis by: Melinda Sanders M.D. (T88100M29280)[420]
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