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| Chorangioma | ||
| Etiology •unknown? •hamartomas of primitive chorionic mesenchyme ? •benign tumor of fetal blood vessels? | ||
| Pathogenesis •unknown, | ||
| Epidemiology • occurs in approximately 1% of pregnancies | ||
| General Gross Description •when arise from villous tissue-usually close to the fetal surface, may bulge from placental surface •can arise from umbilical cord •well circumscribed •cut surfaces are fleshy, congested (red) •if infarcted, cut surface is tan •Examples: | ||
| General Microscopic Description •external surface of tumor is covered by syncytiotrophoblasts •tumor resembles overgrown villus with extensive proliferation of vessels •may be infarcted with loss of nuclear detail •Examples: | ||
| Clinical Correlation •small tumors--asymptomatic •large tumors--associated with hydramnios, antepartum hemorrhage, AV shunts that can lead to fetal heart failure, consumptive coagulopathy, microangiopathic hemolytic anemia | ||
| References •Benirschke,Kurt and Kaufmann,Peter Pathology of the Human Placenta, 2nd edition, New York: Springer-Verlag, 1990, p841-846. •Cunningham et al Williams Obstetrics, 19th edition Norwalk: Appleton and Lange, 1993, p759. Please be patient during transfer. Medline will open in a new window. To return, close the Medline Window Chorangioma
| Synopsis by: Linda Ernst (T88100M91200)[228]
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