Prev
GYN Menu
PathWeb Home
©
Feed Back
About
Next
Chorangioma
Etiology

unknown?
hamartomas of primitive chorionic mesenchyme ?
benign tumor of fetal blood vessels?
Pathogenesis

unknown,
Epidemiology

occurs in approximately 1% of pregnancies
General Gross Description

when arise from villous tissue-usually close to the fetal surface, may bulge from placental surface
can arise from umbilical cord
well circumscribed
cut surfaces are fleshy, congested (red)
if infarcted, cut surface is tan
•Examples:
Placental Chorangioma Chorioangioma
General Microscopic Description

external surface of tumor is covered by syncytiotrophoblasts
tumor resembles overgrown villus with extensive proliferation of vessels
may be infarcted with loss of nuclear detail
•Examples:
Chorangioma (10X) Chorangioma (20x) Chorangioma  (40x) Chorangioma - Infarcted 10x Chorangioma - infarcted 20x Chorangioma - Infarcted 40x
Clinical Correlation

small tumors--asymptomatic
large tumors--associated with hydramnios, antepartum hemorrhage, AV shunts that can lead to fetal heart failure, consumptive coagulopathy, microangiopathic hemolytic anemia
References

Benirschke,Kurt and Kaufmann,Peter Pathology of the Human Placenta, 2nd edition, New York: Springer-Verlag, 1990, p841-846.
Cunningham et al Williams Obstetrics, 19th edition Norwalk: Appleton and Lange, 1993, p759.

Search Medline at National Library of Medicine
Please be patient during transfer. Medline will open in a new window. To return, close the Medline Window
Chorangioma
Synopsis by: Linda Ernst (T88100M91200)[228]
Prev
PathWeb Home
©
Feed Back
About
Next