| Schwannoma
|
Etiology
• Unknown
|
Pathogenesis
• Proliferation of Schwann cells,
|
Epidemiology
• Exceedingly rare
|
General Gross Description
• Well circumscribed, homogeneous gray-tan lesions attached to peripheral nerve
•Examples:
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General Microscopic Description
• Composed of cells with delicate, elongated, wavy nuclei with pointed tips
• Cytoplasm is palely eosinophilic
• Regions of the neoplasm may exhibit lining up of the nuclei into bands of nuclei alternating with cytoplasm (Antoni A); bands of nuclei are termed Verocay bodies
• Antoni B regions lack definite arrangement and may have microcysts
•Examples:
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Clinical Correlation
• Benign lesion
|
References
• Rosen PP, Oberman H. Tumors of the Mammary Gland. Washington, AFIP, 1993, pp. 311.
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp.1351-2.
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| Schwannoma
| | Synopsis by: Melinda Sanders M.D. (T04000M95600)[316]
| |