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Schwannoma
Etiology

Unknown
Pathogenesis

Proliferation of Schwann cells,
Epidemiology

Exceedingly rare
General Gross Description

Well circumscribed, homogeneous gray-tan lesions attached to peripheral nerve
•Examples:
Schwannoma of breast
General Microscopic Description

Composed of cells with delicate, elongated, wavy nuclei with pointed tips
Cytoplasm is palely eosinophilic
Regions of the neoplasm may exhibit lining up of the nuclei into bands of nuclei alternating with cytoplasm (Antoni A); bands of nuclei are termed Verocay bodies
Antoni B regions lack definite arrangement and may have microcysts
•Examples:
References

Rosen PP, Oberman H. Tumors of the Mammary Gland. Washington, AFIP, 1993, pp. 311.
Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp.1351-2.

For Most Current Information Search Medline at National Library of Medicine
This link will directly take you to the relevant new literature
Schwannoma
Synopsis by: Melinda Sanders M.D. (T04000M95600)[316]
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