| Tubular Carcinoma
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Etiology
• Unknown
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Pathogenesis
• Unknown; see general discussion of duct carcinoma,
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Epidemiology
• Represents <2% of all breast carcinomas
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General Gross Description
• Usually small (<2 cms), firm to hard lesions
• Stellate
•Examples:
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General Microscopic Description
• Small duct-like structures lined by a single cell layer often with an angular profile on cut section
• Embedded in stroma with increased cellularity and/or collagen and elastin
• Nuclei are generally very bland and closely resemble normal breast duct epithelium
• May be difficult to separate from sclerosing adenosis or radial scar but generally spread outside the confines of enlarged lobules
•Examples:
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Clinical Correlation
• Diagnosis made when 75% of neoplasm in tubular
• Prognosis is excellent
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References
• Rosen PP, Oberman H. Tumors of the Mammary Gland. Washington, AFIP, 1993, pp. 175-181
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| Tubular Carcinoma
| | Synopsis by: Melinda Sanders M.D. (T04000M82113)[308]
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