| Normal Bone Marrow
|
Etiology
• Not applicable.
|
Pathogenesis
• Not applicable.,
|
Epidemiology
• Not applicable.
|
General Gross Description
• Red in the young individual; yellow and fatty in the older individual
•Examples:
|
General Microscopic Description
• In adult life the ratio of marrow elements to fat is 1:1
• Admixture of myeloid cells and erythroid cells in a ratio of 3:1
• Approximately 60% of cells are myeloid precursors including promyelocytes, metamyelocytes, myelocytes (with specific granules) and immature basophils, eosinophils and neutrophils
• Approximately 20% of cells are erythroid precursors with round dark nuclei
• Ten percent of cells are lymphoid including plasma cells
• Scattered megakaryocytes are also seen
• With age the marrow to fat ratio declines
•Examples:
|
References
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 585-586.
For Most Current Information Search Medline at National Library of Medicine
This link will directly take you to the relevant new literature
| Normal Bone Marrow
| | Synopsis by: Melinda Sanders M.D. (T06000M00100)[97]
| |