Proliferation of Schwann cells.,
Generally disease of adults
Associated with sensory nerves, especially the 8th (acoustic neuroma) in an intracranial location, around the spine with extension through the vertebral foramina, or associated with major nerve trunks
|General Gross Description|
Encapsulated neoplasms which can be divided from the intact nerve.
Neoplasms are adjacent to nerve which may splay over it
Firm, gray lesions that may have degenerative changes.
|General Microscopic Description|
Antoni A regions show lining up of delicate wavy nuclei in bands separated by eosinophilic cytoplasm
Rows of nuclei are Verocay bodies
Antoni B regions show less organization.
Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1352.
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||Synopsis by: Melinda Sanders M.D. (TX0500M95600)