A keloid is exuberant scar formed in response to
In a normal scar formation, the fibroblasts bridge the
edges of a wound and permit the epithelium to grow over.
A normal scar is usually a linear structure, often
depigmented and below the level of the surrounding skin.
In a keloid, however, there is disproportionate
proliferation of fibroblasts giving rise to masses of
The scar therefore protrudes above the surface of the
More common in dark-skinned individuals
|General Gross Description|
A large often tender scar, protruding above the level
of the surrounding skin.
|General Microscopic Description|
Histologically, it is characterized by the presence of
numerous proliferating fibroblasts and
large amounts of dense, deeply eosinophilic-staining
Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 90
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|Synopsis by: T.V.Rajan, M.D., Ph.D. (T01000M49720)