| Infarct
|
Etiology
• Thrombosis of splenic arteries, usually embolic
• Non-thrombotic decrease in blood flow in very large spleens
|
Pathogenesis
• Obstruction or compromise of blood flow with necrosis of distal tissue,
|
Epidemiology
• Associated with endocarditis
• Associated with hematologic conditions resulting in very enlarged spleens, such as leukemia
|
General Gross Description
• White, firm lesions which are triangular
• Base of triangle at capsule
•Examples:
|
General Microscopic Description
• Necrotic, hemorrhagic tissue which does not organize
•Examples:
|
References
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 670.
For Most Current Information Search Medline at National Library of Medicine
This link will directly take you to the relevant new literature
| Infarct
| | Synopsis by: Melinda Sanders M.D. (T07000M54700)[414]
| |