|
|
|
|
|
|
|
| Abscess | ||
| Etiology • Secondary to inhalation, particularly of aspirated stomach contents • Unsucessfully treated or untreated bacterial infection • Embolized organisms e.g.from endocarditis • Trauma • Neoplasm • Miscellaneous including unknown | ||
| Pathogenesis • Generally due to necrotizing organisms such as gram positive and gram negative bacteria, as well as fungi, | ||
| Epidemiology • Immunocompromised patients are at risk as are • Individuals prone to aspiration such as alcoholics, comatose patients, or individuals with depressed gag or cough reflex | ||
| General Gross Description • Cavity in the lung with necrotic debris unless drained by bronchial tree • Wall generally irregular and shaggy • Most likely located in right lung if secondary to inhalation • May be anywhere if sequel to bronchopneumonia or septic emboli •Examples: | ||
| General Microscopic Description • Destruction of pulmonary parenchyma • Often contains causative organism • Marked acute inflammation •Examples: | ||
| Clinical Correlation • Cough with purulent sputum and pain • General symptoms such as fever and weight loss • Requires drainage and antibiotics for cure | ||
| References • Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 699-700. Please be patient during transfer. Medline will open in a new window. To return, close the Medline Window Abscess
| Synopsis by: Melinda Sanders M.D. (T28000M46240)[120]
| |
|
|
|
|
|
|